Neural Network Centroid Optimizer
Proprietary to Applied Biosystems - All Rights Reserved.

Gridding: Definition: Given an image of a microarray with a rectangular grid of features, a gridder assigns each grid row/column position with the image position of the proper feature.

Centroid: Definition: The location of a feature’s center given by the gridder.


Smoothed X,Y Intensity Gradient look up tables based on the concept of 
primate visual cortex neuron receptive fields.

Iteratively refined grid centroids.

Features moved by intensity gradient only allowing anomaly to steal neighbors' centroids. 

With spacing constraint.